Charles River - Laboratory Animals: Rat & Mouse Disease Models

Disease Models (Alphabetical Listing)

Strain	Disease Characteristics
Dahl/SS Rat	Insulin Resistance	Hypertension	Hypercholesterolemia
Dahl/SS Rat	Hyperinsulinemia	Hypertriglyceridemia	Nephropathy
Diabetic Mouse db/db	Diabetes
FHH Rat	Pulmonary Hypertension	Hypertriglyceridemia	Hypercholesterolemia
GK Rat	Insulin Resistance	Non Insulin Dependent Diabetic Models (NIDDM)	Nephropathy
GK Rat	Hyperinsulinemia	Fasting Hyperglycemia
JCR Rat	Insulin Resistance	Ischemic & Artherosclerotic Lesions	Nephropathy
	Hyperinsulinemia	Hypertriglyceridemia
	Obesity	Hypercholesterolemia
NOD Mouse	Insulin-dependent Diabetes Mellitus
Obese Mouse ob/ob	Obesity
Obese Prone (OP-CD)	Insulin Resistance	Fasting Hyperglycemia	Obesity
Obese Prone (OP-CD)	Hyperinsulinemia	Hypertension	Hypertriglyceridemia
Obese Resistant (OR-CD)	Insulin Resistance	Fasting Hyperglycemia	Hypertriglyceridemia
Obese Resistant (OR-CD)	Hyperinsulinemia	Hypertension
PCK Rat	Polycystic Kidney Disease
SHHF Rat	Insulin Resistance	Hypertension	Hypertriglyceridemia
	Hyperinsulinemia	Obesity	Hypercholesterolemia
	Non Insulin Dependent Diabetic Models (NIDDM)	Congestive Heart Failure	Nephropathy
SHR Rat	Insulin Resistance	Hypertension	Hypercholesterolemia
SHR Rat	Hyperinsulinemia	Hypertriglyceridemia
SHROB Rat	Insulin Resistance	Obesity	Nephropathy
	Hyperinsulinemia	Hypertriglyceridemia
	Hypertension	Hypercholesterolemia
Stroke Prone SHR Rat	Insulin Resistance	Hypertension	Hypercholesterolemia
Stroke Prone SHR Rat	Hyperinsulinemia	Hypertriglyceridemia	Nephropathy
THE POUND MOUSE^TM	Insulin Resistance	Fasting Hyperglycemia	Hypercholesterolemia
THE POUND MOUSE^TM	Hyperinsulinemia	Obesity
ZDF Rat	Insulin Resistance	Fasting Hyperglycemia	Hypercholesterolemia
	Hyperinsulinemia	Obesity	Nephropathy (Hydronephrosis)
	Non Insulin Dependent Diabetic Models (NIDDM)	Hypertriglyceridemia
ZSF1 Rat	Insulin Resistance	Fasting Hyperglycemia	Hypertriglyceridemia
	Hyperinsulinemia	Hypertension	Hypercholesterolemia
	Non Insulin Dependent Diabetic Models (NIDDM)	Obesity	Nephropathy (Hydronephrosis)
Zucker Rat	Insulin Resistance	Obesity	Hypercholesterolemia
Zucker Rat	Hyperinsulinemia	Hypertriglyceridemia	Nephropathy (Hydronephrosis)

Note: In certain cases, phenotype is expressed or enhanced when the animal is fed a specific diet.

Disease Models Listed by Indication

Datasheet: Disease Models

Datasheet: Cardiovascular Models

Datasheet: Metabolic Disease Models

Datasheet: Renal Disease Models

Disease Model Specifications

Evaluation of Portable Glucometers for Use in Rats

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